Each cap contains Undenatured Type II Collagen (UC-II) 40mg, Boswellia serrata Gum Extract (Aflapin) 100mg. Vylex contains UC-ll, a novel undenatured type II collagen & Aflapin, a novel Boswellia serrata gum extract standardized to 20% AKBA. UC-ll & Aflapin are patented active ingredients & support joint health by their disease-modifying anti-inflammatory & cartilage protecting pathways. Research in multiple clinical trials have shown safety & efficacy in reducing joint pain (from 5-7 days), stiffness & increasing physical function & mobility.

Action: These disease-modifying mechanism of action have been evaluated through multiple pre-clinical studies. i) Activates T regulatory (Treg) cells which increase the production of anti-inflammatory mediators such as IL-4, IL-10 & TGF-β, which in turn, stimulate chondrocytes to synthesize cartilage matrix components. ii) Inhibits production of cartilage degrading enzymes, matrix metalloproteinases MMP-3 & MMP-13, which prevents cartilage breakdown. iii) Reduce the production of pro-inflammatory mediators such as 5-lipooxygenase (5-LOX), IL-1β, TNF-α, IL-2 & IL-17